Package: blisa 1.0.2

Yunshun Chen

blisa: Infer Cell-Cell Communication from Spatial Transcriptomics

Identifies cell-cell communication hotspots in spatial transcriptomics data using bivariate Local Moran's I statistics on hexagonally binned cells. Provides functions for spatial weighting, ligand-receptor pair filtering, hotspot detection, and visualisation of sender-receiver cell-type interactions.

Authors:Yunshun Chen [aut, cre], Lei Qin [aut], Lizhong Chen [aut]

blisa_1.0.2.tar.gz
blisa_1.0.2.zip(r-4.7-any)blisa_1.0.2.zip(r-4.6-any)blisa_1.0.2.zip(r-4.5-any)
blisa_1.0.2.tgz(r-4.6-any)blisa_1.0.2.tgz(r-4.5-any)
blisa_1.0.2.tar.gz(r-4.7-any)blisa_1.0.2.tar.gz(r-4.6-any)
blisa_1.0.2.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
blisa/json (API)

# Install 'blisa' in R:
install.packages('blisa', repos = c('https://chenlaboratory.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/chenlaboratory/blisa/issues

Pkgdown/docs site:https://chenlaboratory.github.io

On CRAN:

Conda:

5.15 score 2 scripts 401 downloads 14 exports 96 dependencies

Last updated from:f1caa1bfcb. Checks:7 WARNING, 2 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develWARNING205
source / vignettesOK263
linux-releaseWARNING233
macos-releaseWARNING232
macos-oldrelWARNING196
windows-develWARNING148
windows-releaseWARNING130
windows-oldrelWARNING122
wasm-releaseOK140

Exports:blisablisaPathwaycomputeSpatialWeightsfilterLRpairshexBinCellsis.blisaplotCCIplotCCILRplotCCIspatialplotCCIsummaryplotHotspotsplotLRrankrunCCIvisiumSpotBins

Dependencies:abindaskpassBiobaseBiocFileCacheBiocGenericsbitbit64blobbootcachemcirclizeclassclassIntcliclueclustercodetoolscolorspaceComplexHeatmapcpp11crayoncurlDBIdbplyrDelayedArraydeldirdigestdoParalleldplyre1071farverfastLISAfastmapfilelockforeachgenericsGenomicRangesGetoptLongggplot2GlobalOptionsgluegtablehttr2IRangesisobanditeratorsKernSmoothlabelinglatticelifecyclemagickmagrittrMatrixMatrixGenericsmatrixStatsmemoiseopensslpillarpkgconfigpngproxypurrrR6RColorBrewerRcpprjsonrlangRSQLites2S4ArraysS4VectorsS7scalesSeqinfosfshapeSingleCellExperimentspSparseArraySpatialExperimentspDataspdepstringistringrSummarizedExperimentsystibbletidyrtidyselectunitsutf8vctrsviridisLitewithrwkXVector

Visium profile of human breast tumour
Introduction | Load Package | Load Example Data | Quality control | Run BLISA at the LR level | Run BLISA at the pathway level | Visualization | Spatial Map of Hotspot Bins | Session Information
Rendered fromvisium.Rmdusingknitr::rmarkdown

Last update: 2026-08-11
Started: 2026-08-11

Exploring cell-cell interaction with blisa
Introduction | Load Package | Load Example Data | Bin Cells into Hexagons | Run BLISA | Rank LR Pairs by Hotspot Count | Spatial Map of Hotspot Bins | Cell-Cell Interaction (CCI) Heatmaps | Across all LR pairs | For a single LR pair | Aggregated across LR pairs | Spatial Map of Dominant Cell-Type Pairs | Session Information
Rendered fromxenium.Rmdusingknitr::rmarkdown

Last update: 2026-08-11
Started: 2026-08-11